This will be a reunion for Bautista and Dune director Denis Villeneuve, as they worked together on Blade Runner 2049.
In the film, Chalamet plays Paul Atreides, in a world where a drug called Melange is causing many feudal families to compete for control over the substance. The drug elongates your life span and gives you a heightened consciousness as well as making interstellar travel possible; however, it also is extremely addictive and deadly. The planet of Arrakis, or "Dune", is the only place where you can find it.
Bautista can next be seen in Marvel's Avengers: Endgame in April.