Deep Blue Sea (1999)

Scientist, Susan McCallister, has been experimenting with the brains of mako sharks, cold-blooded killing machines known for their speed and ferocity. Violating all ethical codes, she has genetically re-engineered their DNA, creating massive, super-fast, highly intelligent creatures - with attitude. When a storm hits the floating laboratory, the sharks escape their tank, stalk the crew, and unleash a reign of terror more frightening than your worst nightmare.